Theology as an exercise in continual renovation must be renewed permanently from its sources and in dialogue with the signs of the times. In this regard, Balthasar said that the principal problem of contemporary theology was the separation of theology and spirituality. Two aspects that was united in the thinking of the Fathers of the church. This work shows this problem in contemporary theology, especially in Latin American context and builds a bridge with the Christian eastern tradition present in Gregory of Nyssa. From an analysis of the Homilies on the Song of Songs and the Life of Moses, the research seeks to prove the possibility of understanding the theological work of Gregory in the conceptual framework of the categories μυστήριον, μυσταγωγία, μυστικά, γνรณφος, ἀκολουθία and ἐπέκτασις - categories that could allow a synthesis between theology and spirituality and could be a contribution to the renovation of theology today.
